Just like previous Grand Theft Auto games, when you have a sniper, you can shoot the moon and it changes sizes.
Frank Vincent (Don Salvatore Leone) is the only prominent actor to reprise his role from Grand Theft Auto III (2001), aside from Sondra James (Ma Cipriani) and Guru (8-Ball) who return in small roles, as well as returning radio characters. Other returning characters from GTA III were voiced by different actors. Vincent is also billed first in both games, despite the protagonist having a voice this time, unlike in GTA III where he is silent.
First time motorcycles have been used in Liberty City.
When you look at the game map, it is the first time you can see a complete overview of the Liberty City map in game as you couldn't see a complete layout of the same map in Grand Theft Auto III (2001).
Was originally released on the Sony PlayStation Portable (PSP) in October 2005, and later released for the PlayStation 2 in June 2006.