- Sharon Osbourne: Ozzy and I are very happy to be here tonight.
- Ozzy Osbourne: I'm happy to be anywhere.
- Ellen DeGeneres: I'm really happy to be here, although I don't sing or play an instrument. Well, I play my stereo, which really isn't a musical instrument, but I can say that I play my stereo because that's what I do to listen to music. Those who don't like music are stupid. That's right, I said stupid, but they're not watching. I like all kinds of music... well, except for polka, because it's too fast for me. But I like some of it, I like a lot of it.
- Matthew Perry: John, I'm glad that you think that way, because I also think that my body is a temple.
- John Mayer: I didn't write that song for you.
- Matthew Perry: Yes, you did.
- John Mayer: No, I didn't.
- Matthew Perry: Well, let's not fight in front of the audience.
- Matthew Perry: For this category, we have to say that, sadly, there are no duos nominated.
- John Mayer: Over the past year, we've been touring the country, but three weeks ago, we decided to split up due to our differences.
- Matthew Perry: Yeah, it turns out that John is musical, and I'm not. And even if we'll end up suing each other, we'll still be good friends.
- Steven Tyler: It's a real honor to be presenting this award with the legendary B.B. King.
- B.B. King: Thank you, boys. That means a lot to me. I got to tell you, I've been an Aerosmith fan since, well, I was a boy.