MythBusters (2003) proved that it is possible to stop a sulfuric acid leak using chocolate just like in this episode.
The helicopter that brings Mac to the remote lab site is the same helicopter (N51BT) that was used in the Blue Thunder movie and TV Series.
The cave entrance to the underground lab seen in the beginning is the same entrance seen years later in Richard Dean Anderson's next big series Stargate SG-1 (1997).
The reason these laboratory sets in this Paramount pilot episode look familiar is because they are redresses from Paramount's "Star Trek Wrath of Khan" from 1982. The most intact set shows the Enterprise's photon torpedo room with launch tube door.