During filming a crew member commented to Martin Kemp what a great job the makeup department had done on the prosthetics that made it look like the veins in his forehead were bulging out. Kemp was confused, as he was not wearing any prosthetic makeup. The bulging veins were actually the result of an undiagnosed brain tumor.
Because of this film's success, Anne Goursaud and Alyssa Milano decided to shoot another erotic film: Poison Ivy II (1996): Lily.
Anne Goursaud feared that the extras would feel uptight while shooting the orgy scene. Therefore, she cast mainly people who were real life couples.
Alyssa Milano's first on-screen nude scene, though she had posed totally nude for the premiere issue of Bikini magazine in 1993 before making this film in order to, according to her, break away from the sweet young girl roles she kept getting offered. She said the nude appearances taught her to begin requiring a nudity clause in her contracts giving her "full control" over all her nude scenes. In a 1995 interview, she explained her motivation for some explicit scenes in Embrace of the Vampire: "I'm not going to say that I was manipulated into doing things that I didn't want to do. I did it because it was a woman director and I felt protected. And I learned a lot as far as knowing where the camera is and what coverage they need so that it's not all explicit."