Porn stars Randy West, Tom Byron, Amber Lynn, Sharon Mitchell, Ron Jeremy, Herschel Savage, Erica Boyer, Barbara Dare, Cara Lott and Jamie Gillis appear in the film during the party sequence.
Adult film actress Seka mentions in her official biography that she auditioned for a small part as an extra in the porn party sequence, but ultimately passed on being in this film after director John Frankenheimer asked her out for a dinner date.
Second of two movie adaptations of an Elmore Leonard novel. The book had been adapted as The Ambassador (1984) a couple years earlier. Both pictures were produced by Menahem Golan and Yoram Globus and The Cannon Group. Of the two, Leonard wrote the screenplay for only one of them - 52 Pick-Up (1986).
Roy Scheider had been offered the lead in several of Cannon's films before but turned them down until they offered him the lead role in the film adaption of Elmore Leonard's "52 Pick-Up," which he accepted simply because he liked the book.
The baseball game at Dodger Stadium in one scene was a real one, between the Los Angeles Dodgers and the New York Mets on Friday, May 16, 1986. The Dodgers won 4-3 in 11 innings.