- Named a Disney Legend. (2004)
- The late actor Charles Laughton was her godfather.
- Sister-in-law of actor Edward Woodward.
- Her husband, Ned Nalle, became a senior executive at Universal Studios. Karen and Ned were married in a Philadelphia church, where his ancestors worshiped. From 2008-11, he served as an executive producer at ABC Studios, and now produces and distributes television series for various television networks.
- Last performed in a stage production of "Othello" in 1981 playing Desdemona opposite James Earl Jones and Christopher Plummer.
- Children's names: Garrick William Hyde-White (1990, by Alex Hyde-White), Isabella Bella Nalle (1995) and Griffin Nalle (1996) (by Edwin Ned Nalle).
- Worked in a friend's art gallery after giving up acting.
- Former daughter-in-law of Wilfrid Hyde-White.
- Auditioned for the role of the Grand Duchess Anastasia Romanov in Nicholas and Alexandra (1971) but lost out to Fiona Fullerton.
- Aunt of Emily Woodward.
- Her daughter, Isabella Bella Nalle, made an uncredited appearance in The Invincible Sword (2005) with her in 2005, playing "Jacqueline/Jacques" as a child.
- Along with Dick Van Dyke, she is one of just two actors to appear in both Mary Poppins (1964) and Mary Poppins Returns (2018).
- In 1970 she started making the film Capri for Ken Annakin with Michael Gough, Zena Walker and Jack Watling but finance for it ran out.
- Karen Dotrice, Julie Andrews, and Dick Van Dyke are the only living stars of "Mary Poppins" as of January 2024, when Glynis Johns passed away at the age of 100.
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