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- CreatorConstance M. BurgeStarsHolly Marie CombsAlyssa MilanoBrian KrauseThree Halliwell sisters discover that they are descendants of a line of good female witches and are destined to fight against the forces of evil, using their combined power of witchcraft known as the "Power of Three".
- CreatorPaul T. ScheuringStarsDominic PurcellWentworth MillerAmaury NolascoA structural engineer installs himself in a prison he helped design, in order to save his falsely accused brother from a death sentence by breaking themselves out from the inside.
- CreatorPosie Graeme-EvansCaroline StantonStarsAaron JefferyRachael CarpaniSimmone MackinnonEstranged sisters Claire and Tess are reunited after 20 years when they inherit their family's cattle station, "Drover's Run", in the outback of South Australia, following their father's death.
- CreatorMark SchwahnStarsChad Michael MurrayJames LaffertyHilarie Burton MorganHalf-brothers Lucas and Nathan Scott trade between kinship and rivalry both on the basketball court and in the hearts of their friends in the small, but not so quiet town of Tree Hill, North Carolina.
- CreatorAlfred GoughMiles MillarStarsTom WellingMichael RosenbaumAllison MackA young Clark Kent struggles to find his place in the world as he learns to harness his alien powers for good and deals with the typical troubles of teenage life in Smallville, Kansas.
- CreatorRob ThomasStarsKristen BellJason DohringEnrico ColantoniAfter her best friend is murdered, and her father is removed as county Sheriff, Veronica Mars dedicates her life to cracking the toughest mysteries in the affluent town of Neptune.
- CreatorStephen ChboskyJosh SchaerJonathan E. SteinbergStarsSkeet UlrichLennie JamesAshley ScottA small town in Kansas is literally left in the dark after seeing a mushroom cloud over nearby Denver, Colorado. The townspeople struggle to find answers about the blast and solutions on how to survive.
- CreatorJason KatimsStarsShiri ApplebyJason BehrKatherine HeiglThe lives of three young alien/human hybrids with extraordinary gifts in Roswell.
- CreatorJosh SchwartzStarsMischa BartonAdam BrodyPeter GallagherA troubled youth becomes embroiled in the lives of a close-knit group of people in the wealthy, upper-class neighborhood of Newport Beach, Orange County, California.
- CreatorDarren StarStarsJason PriestleyShannen DohertyLuke PerryA group of friends living in Beverly Hills, California make their way through life from their school days into adulthood.
- CreatorRachel LangJames GriffinStarsRobyn MalcolmAntony StarrSiobhan MarshallWhen career criminal Wolfgang West gets put away for four years, his wife Cheryl decides it's time for her family to go straight. But can the Wests change the habits of a lifetime?
- CreatorEric KripkeStarsJared PadaleckiJensen AcklesJim BeaverTwo brothers follow their father's footsteps as hunters, fighting evil supernatural beings of many kinds, including monsters, demons, and gods that roam the earth.
- CreatorAdam DiVelloStarsAudrina PatridgeHeidi MontagSpencer PrattAfter high school graduation, "Laguna Beach" alumna Lauren sets out to live on her own in Los Angeles and work as an intern at Teen Vogue.
- CreatorJon Robin BaitzStarsDave AnnableCalista FlockhartRachel GriffithsThe story of the drama surrounding a family's adult siblings.
- CreatorShonda RhimesMichelle LirtzmanStarsEllen PompeoChandra WilsonJames Pickens Jr.A drama centered on the personal and professional lives of five surgical interns and their supervisors.
- CreatorJohn GrayStarsJennifer Love HewittDavid ConradCamryn ManheimMelinda Gordon, a newly married woman, possesses the gift of communicating with the dead. With her best friend Andrea's assistance, she helps the earthbound spirits to find peace and cross over.
- CreatorStephanie SavageJosh SchwartzStarsBlake LivelyLeighton MeesterPenn BadgleyPrivileged teens living on the Upper East Side of New York can hide no secret from the ruthless blogger who is always watching.
- CreatorHart HansonStarsEmily DeschanelDavid BoreanazMichaela ConlinF.B.I. Special Agent Seeley Booth teams up with the Jeffersonian's top anthropologist, Dr. Temperance Brennan, to investigate cases where all that's left of the victims are their bones.
- CreatorMichael BerkGregory J. BonannDouglas SchwartzStarsDavid HasselhoffPamela AndersonYasmine BleethAt a Los Angeles beach, a team of lifeguards led by Lieutenant Mitch Buchannon save lives, deal with personal dramas, fight crime and participate in over the top adventures on a daily basis.
- CreatorBrenda HamptonStarsStephen CollinsCatherine HicksJessica BielEric Camden, a minister, and his wife Annie deal with the drama of having seven children, ranging from toddlers to adults with families of their own.
- CreatorMichael CrichtonStarsAnthony EdwardsGeorge ClooneyJulianna MarguliesThe doctors who work in the ER at the County General Hospital in Chicago grapple with ups and downs in their personal and professional lives while trying to give apt medical care to their patients.
- CreatorChristopher KeyserAmy LippmanStarsMatthew FoxScott WolfNeve CampbellFive siblings raise each other following their parents' untimely deaths.
- CreatorKevin WilliamsonStarsJames Van Der BeekKatie HolmesMichelle WilliamsTwo childhood best friends, Dawson and Joey, go through different stages of adolescence together. Their friendship is later tested when they both start a relationship with different people.
- CreatorCarmen FinestraDavid McFadzeanMatt WilliamsStarsTim AllenEarl HindmanTaran Noah SmithThe daily trials and tribulations of Tim "The Tool Man" Taylor, a television show host raising three mischievous boys with help from his loyal co-host, loving wife, and eccentric neighbor.
- CreatorJeff FranklinStarsBob SagetJohn StamosDave CoulierA widowed sportscaster raises his three daughters with assistance from his rock and roll brother-in-law and madcap best friend.